RED1 Antibody

Western Blot: RED1 Antibody [H00000104-B01P] - Analysis of ADARB1 expression in human kidney.

Immunocytochemistry/Immunofluorescence: RED1 Antibody [H00000104-B01P] - Analysis of purified antibody to ADARB1 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: RED1 Antibody [H00000104-B01P] - Expression in HepG2.

Western Blot: RED1 Antibody [H00000104-B01P] - Analysis of ADARB1 expression in transfected 293T cell line by ADARB1 polyclonal antibody. Lane 1: ADARB1 transfected lysate(81.51 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

RED1 Antibody Summary

• Immunogen: ADARB1 (NP_056648.1, 1 a.a. - 741 a.a.) full-length human protein. MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP
• Specificity: Reacts with adenosine deaminase, RNA-specific, B1 (RED1 homolog rat).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ADARB1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
• Application Notes: This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RED1 Antibody

• ADAR2a
• ADAR2ADAR2g
• ADAR2a-L1
• ADAR2a-L2
• ADAR2a-L3
• ADAR2b
• ADAR2c
• adenosine deaminase, RNA-specific, B1
• double-stranded RNA-specific editase 1
• DRABA2
• DRADA2hRED1
• EC 3.5
• human dsRNA adenosine deaminase DRADA2
• human dsRNA adenosine deaminase DRADA2b, EC 3.510adenosine deaminase, RNA-specific, B1 (homolog of rat RED1)
• RED1 homolog
• RED1ADAR2d
• RNA editase
• RNA editing deaminase 1
• RNA-editing deaminase 1
• RNA-editing enzyme 1
• RNA-specific, B1 (RED1 homolog rat)

Background

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADARB1
• Entrez:
  • 104(Human)
• Uniprot:
  • NP_056648.1(Human)