GluR2 Antibody (3A11) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: GluR2 Antibody (3A11) - Azide and BSA Free [NBP2-29731] - Mouse anti-GluR staining of adult monkey pryamidal cells.

• Reactivity: Hu, Rt, Pm
• Applications: WB, ELISA, Func, ICC/IF, IHC, IP
• Clone: 3A11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.7 mg/ml

GluR2 Antibody (3A11) - Azide and BSA Free Summary

• Description: Relevant Entrez Gene Numbers: NM_000839.2
• Immunogen: Recombinant fusion protein TrpE-GluR2.
• Specificity: Glutamate Receptor 2 (GluR2) by Western Blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRIA2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:500-1000
  • Immunoprecipitation 1:10-1:500
  • Radioimmunoassay 1:100-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: Immunohistochemistry on 4% paraformaldehyde fixed tissue.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.7 mg/ml
• Purity: Protein A or G purified

Notes

Relevant Entrez Gene Numbers: NM_000839.2

Alternate Names for GluR2 Antibody (3A11) - Azide and BSA Free

• AMPA 2
• AMPA2
• GluA2
• GluR2
• GLURB
• GluR-K2
• glutamate receptor, ionotropic, AMPA 2
• GRIA2
• HBGR2

Background

The GRIA2 gene encodes for glutamate receptor 2 with an isoform flop of 883 amino acids, 98 kDA, isoform flip of 883 amino acids and 98 kDA, and an isoform 3 of 901 amino acids long and 100 kDA. Glutamate receptors function as a ligand-gated ion channel in the central nervous system and are the predominant excitatory neurotransmitter receptors in the brain. GRIA2 has been researched regarding its role in Alzheimer's disease, multiple sclerosis, motor neuron disease, epilepsy, anorexia, bioplar disorder, and neurodegeneration. GRIA2 is involved in the CREB pathway, intracellular calcium signaling, glutamic acid signaling, and calcium channels as well as interacts with genes NSF, GRIA3, DLG4, GRID2, and SDCBP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIA2
• Uniprot:
  • Q14416()