GLUD1/GLUD2 Antibody (848209) [Alexa Fluor™ Plus 405]

• Reactivity: Hu, Mu, Rt
• Clone: 848209
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

GLUD1/GLUD2 Antibody (848209) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human, mouse and rat GLUD1/GLUD2 in ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GLUD1/GLUD2 Antibody (848209) [Alexa Fluor™ Plus 405]

• epididymis secretory sperm binding protein
• epididymis tissue sperm binding protein Li 18mP
• GDH
• GDH1
• GLUD
• GLUD1/GLUD2
• glutamate dehydrogenase (NAD(P)+)
• glutamate dehydrogenase 1, mitochondrial
• hGDH1

Background

Glutamate dehydrogenase 2 (GLUD2 or GDH2) is an approximately 58 kDa mitochondrial enzyme that catalyzes the reversible interconversion of glutamate to alpha‑ketoglutarate and ammonia. This activity is important in glutamine and ammonia metabolism as well as glutamatergic signal transduction. In contrast to the widely expressed GLUD1, GLUD2 expression is restricted to testicular Sertoli and Leydig cells, brain astrocytes, and renal tubule epithelial cells. GLUD2 and GLUD1 are synthesized with N-terminal mitochondrial transit peptides. Within amino acids 58-558, human GLUD2 and GLUD1 share 97% aa sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.