GLP-1R Antibody


Western Blot: GLP-1R Antibody [NLS1205] - WB detection of GLP-1R in lysates of human (1) pancreas (2) lung and (3) kidney tissues using 2 ug/mL concentration of GLP-1R antibody.
Immunohistochemistry: GLP-1R Antibody [NLS1205] - Analysis of GLP-1R in mouse pancreas.
Immunohistochemistry: GLP-1R Antibody [NLS1205] - Human pancreas (Islets of Langerhans).
Simple Western: GLP-1R Antibody [NLS1205] - Image shows a specific band for GLP-1R in 0.5 mg/mL of HEK293 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Simple Western, IHC, IHC-P
1.0 mg/ml

GLP-1R Antibody Summary

A synthetic peptide made to an N-terminal extracellular portion of the human GLP1R protein (between residues 100-200). [UniProt P43220]
Cell membrane
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1 - 2 ug/mL
  • Simple Western 1:50
  • Immunohistochemistry 10 - 20 ug/mL
  • Immunohistochemistry-Paraffin 10 - 20 ug/mL
Application Notes
In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Pancreas Lysate (NB820-59244)
Control Peptide
GLP-1R Peptide (NLS1205PEP)
Read Publications using
NLS1205 in the following applications:

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for GLP-1R Antibody

  • GLP-1 receptor
  • GLP1R
  • GLP-1R
  • GLP-1-R
  • glucagon-like peptide 1 receptor
  • MGC138331


GLP1R, a Glucagon Receptor, has been suggested to affect the feelings of satiety or hunger, sensation of glucose levels, control of glucagon sensitivity of islets, and non insulin-dependent diabetes mellitus. Glucagon-like peptide 1 is an incretin hormone produced by enteroendocrine L-cells in the intestinal mucosa. The hormone is released in response to food intake and plays an important role in maintaining blood glucose homeostasis. Stimulation of the GLP-1R by endogenous hormone induces multiple complementary mechanisms, which together result in a lowering of circulating blood glucose levels. These mechanisms include receptor-mediated enhancement of glucose-induced insulin secretion from pancreatic -cells, inhibition of gastric emptying with a delay in the gastrointestinal resorption of nutrients, inhibition of glucagon secretion, and inhibition of food intake. Desensitization of GLP1R on pancreatic beta-cells is one of the causes of non insulin-dependent diabetes mellitus (NIDDM). GLP1R knockout mice are viable, develop normally, but exhibit increased levels of blood glucose following oral glucose challenge in association with diminished levels of circulating insulin. Recently it has been shown that overexpression of glucagon-like peptide-1 receptor improves learning in rats (During et al. 2003). GLP1R has been reported in pancreas, brain, heart, kidney, lung, and stomach. ESTs have been isolated from kidney and skin libraries.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
Species: Hu, Mu
Applications: CyTOF-ready, ICC, ICFlow
Species: Hu
Applications: IHC
Species: Hu
Applications: WB, Simple Western, IHC, ICC
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB
Species: Hu, Mu
Applications: WB, IHC, IP, DirELISA
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, CyTOF-ready, ICFlow
Species: Hu
Applications: Flow, IHC, Block, CyTOF-ready
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P

Publications for GLP-1R Antibody (NLS1205)(4)

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: IHC-P.

Filter By Application
All Applications
Filter By Species
All Species
Showing Publications 1 - 4 of 4.
Publications using NLS1205 Applications Species
Kimura T, Obata A, Shimoda M et al. Decreased glucagon-like peptide 1 receptor expression in endothelial and smooth muscle cells in diabetic db/db mice: TCF7L2 is a possible regulator of the vascular glucagon-like peptide 1 receptor Diab Vasc Dis Res 2017 Aug 01 [PMID: 28830217] (Mouse) Mouse
Karabulut S, Coskun ZM, Bolkent S. Immunohistochemical, apoptotic and biochemical changes by dipeptidyl peptidase-4 inhibitor-sitagliptin in type-2 diabetic rats. Pharmacol Rep 2015 Oct [PMID: 26398375] (Rat) Rat
Matveyenko AV, Dry S, Cox HI et al. Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 Diabetes: Interactions With Metformin. Diabetes;58(7):1604-1615. 2009 [PMID: 19403868]
Karabulut S, Coskun ZM, Bolkent S. Immunohistochemical, apoptotic and biochemical changes by dipeptidyl peptidase-4 inhibitor-sitagliptin in type-2 diabetic rats Pharmacological Reports. 2015 Feb 01 (IHC-P, Rat)

GLP-1R antibody used at 1:50 dilution for IHC-P application on formalin fixed paraffin embedded (10% formalin-PBS for 24 hours at 4C) pancreatic tissue samples from Rats which were subjected or not to streptozotocin /STZ-induced diabetes and/or treatment with dipeptidyl peptidase-4 inhibitor-sitagliptin. Signal detection was carried out using streptavidin-biotin-peroxidase method with histostain-plus bulk kit and 3-amino-9-ethyl-carbazole/AEC substrate kit (Fig 5).

Reviews for GLP-1R Antibody (NLS1205) (0)

There are no reviews for GLP-1R Antibody (NLS1205). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

View specific protocols for GLP-1R Antibody (NLS1205): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for GLP-1R Antibody (NLS1205) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Additional Array Products

Bioinformatics Tool for GLP-1R Antibody (NLS1205)

Discover related pathways, diseases and genes to GLP-1R Antibody (NLS1205). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for GLP-1R Antibody (NLS1205)

Discover more about diseases related to GLP-1R Antibody (NLS1205).

Pathways for GLP-1R Antibody (NLS1205)

View related products by pathway.

PTMs for GLP-1R Antibody (NLS1205)

Learn more about PTMs related to GLP-1R Antibody (NLS1205).

Research Areas for GLP-1R Antibody (NLS1205)

Find related products by research area.

Blogs on GLP-1R

There are no specific blogs for GLP-1R, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our GLP-1R Antibody and receive a gift card or discount.


Gene Symbol GLP1R