Ghrelin/Obestatin Antibody (226710) [DyLight 405]

• Reactivity: Hu
• Applications: ELISA
• Clone: 226710
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

Ghrelin/Obestatin Antibody (226710) [DyLight 405] Summary

• Immunogen: Synthetic peptide containing human Ghrelin/Obestatin
  Accession # Q9UBU3
• Specificity: Detects human Ghrelin/Obestatin in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Ghrelin/Obestatin Antibody (226710) [DyLight 405]

• appetite-regulating hormone
• ghrelin
• ghrelin/obestatin preprohormone
• ghrelin/obestatin prepropeptide
• Ghrelin/Obestatin
• Growth hormone secretagogue
• Growth hormone-releasing peptide
• Motilin-related peptide
• MTLRPgrowth hormone secretagogue receptor ligand
• obestatin
• Protein M46

Background

Ghrelin is a 28 residue pepetide expressed by stomach cells that is responsible for the hunger sensation. Expression is increased during times of fasting, and decreased after food consumption. Ghrelin is initially derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Ghrelin antibodies are useful tools for lipid and metabolism research as well as neuroscience studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.