Ghrelin Receptor/GHSR Antibody (502430) [Unconjugated]

HEK293 human embryonic kidney cell line transfected with human GHSR and eGFP was stained with either (A) Mouse Anti-Human GHSR Monoclonal Antibody (Catalog # MAB8370) or (B) Mouse IgG1 Isotype Control (Catalog # MAB002) followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 502430
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Ghrelin Receptor/GHSR Antibody (502430) [Unconjugated] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human GHSR
  Accession # NP_940799
• Specificity: Detects GHSR on transfectants by flow cytometry.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GHSR
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Ghrelin Receptor/GHSR Antibody (502430) [Unconjugated]

• GH-releasing peptide receptor
• Ghrelin receptor
• GHRP
• GHSR
• GHS-R
• growth hormone secretagogue receptor type 1
• growth hormone secretagogue receptor

Background

GHSR is a member of the G protein-coupled receptor family that may play a role in energy homeostasis and regulation of body weight. Two conserved transcript variants for GHSR are expressed in several tissues. This transcript, 1a, excises an intron and encodes the functional protein. GHSR is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. Mutations in GHSR are associated with autosomal idiopathic short stature.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GHSR
• Uniprot:
  • NP_940799()