Gastrokine 1 Antibody

Western Blot: Gastrokine 1 Antibody [NBP2-24766] - Analysis of GKN1 in human stomach tissue lysate using this antibody. 1 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

• Reactivity: Hu, Po, Eq, Pm, Mu, Bv, Ca
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Gastrokine 1 Antibody Summary

• Description: Novus Biologicals Rabbit Gastrokine 1 Antibody (NBP2-24766) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The portions of amino acids range between 100-150 of human GKN1 was used as the immunogen.
• Predicted Species: Mouse (94%), Bovine (94%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GKN1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1-0.2 ug/ml

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in chimpanzee and dog, 94% homologous in mouse and cow, 88% homologous in rat and 77% homologous in chicken.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for Gastrokine 1 Antibody

• 18 kDa antrum mucosa protein
• AMP18
• AMP-18
• AMP18BRICHOS domain containing 1
• BRICD1
• CA11
• CA11MGC70354
• FOV
• Foveolin
• Gastrokine 1
• gastrokine-1
• GKN1
• Protein CA11

Background

GKN1, also known as Gastrokine-1, is a 199 amino acid that is approx. 22 kDa, found to be expressed in stomach; has been shown to have mitogenic activity and may be influencing gastric mucosal epithelium. Studies on this protein have shown a relationship with the following diseases and disorders: patent ductus arteriosus, congenital diaphragmatic hernia, respiratory failure, pulmonary hypertension, hernia, gastric cancer, hypertension, gastritis colorectal cancer, and adenocarcinoma. This protein has been linked to positive regulation of cell proliferation, positive regulation of cell division, and digestion pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GKN1