Gas6 Antibody [DyLight 594]

• Reactivity: Mu
• Applications: IHC, ELISA, ELISA(Cap), ELISA(Det)
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 594

Gas6 Antibody [DyLight 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Gas6 (R&D Systems, Catalog # 986-GS)
  Asp115-Pro673
  Accession # CAA42507
• Specificity: Detects mouse Gas6 in ELISAs and Western blots. In sandwich immunoassays, less than 10% cross-reactivity with recombinant human Gas6 is observed and less than 1% cross-reactivity with recombinant mouse Gas1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GAS6
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Gas6 Antibody [DyLight 594]

• AXLLG
• AXLLGAXL stimulatory factor
• AXSFAXL receptor tyrosine kinase ligand
• DKFZp666G247
• FLJ34709
• Gas6
• GAS-6
• growth arrest-specific 6
• growth arrest-specific protein 6

Background

Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GAS6