gamma C Crystallin Antibody (OTI1D6) [CoraFluor™ 1]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI1D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

gamma C Crystallin Antibody (OTI1D6) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Full length human recombinant protein of human CRYGC(NP_066269) produced in HEK293T cell.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: gamma C Crystallin
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: >95%

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for gamma C Crystallin Antibody (OTI1D6) [CoraFluor™ 1]

• CCL
• CRYG3gamma-C-crystallin
• crystallin, gamma C
• crystallin, gamma-3
• Gamma-C-crystallin
• Gamma-crystallin 2-1
• Gamma-crystallin 3
• gamma-crystallin C

Background

Gamma-crystallin C, or CRYGC for short, contains a 174 amino acid isoform that is 21 kDa, and is involved in supporting the eye lens through its highly symmetrical and organized gene cluster. Research has found that defects in the protein are a cause of autosomal dominant cataracts, and current research is being conducted to determine the protein's relation to a variety of other diseases and disorders, including variable zonular pulverulent cataract, coppock-like cataract, blindness, pneumonia, ADHD, bronchitis, and cancer. Gamma-crystallin C has been linked to eye development and visual perception, and interacts with proteins such as CRYAA, CRYBB2, CRYAB, and HSPB1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: gamma C Crystallin