gamma C Crystallin Antibody (OTI1D6) [Alexa Fluor® 750]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI1D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

gamma C Crystallin Antibody (OTI1D6) [Alexa Fluor® 750] Summary

• Immunogen: Full length human recombinant protein of human CRYGC(NP_066269) produced in HEK293T cell.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: gamma C Crystallin
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: >95%

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for gamma C Crystallin Antibody (OTI1D6) [Alexa Fluor® 750]

• CCL
• CRYG3gamma-C-crystallin
• crystallin, gamma C
• crystallin, gamma-3
• Gamma-C-crystallin
• Gamma-crystallin 2-1
• Gamma-crystallin 3
• gamma-crystallin C

Background

Gamma-crystallin C, or CRYGC for short, contains a 174 amino acid isoform that is 21 kDa, and is involved in supporting the eye lens through its highly symmetrical and organized gene cluster. Research has found that defects in the protein are a cause of autosomal dominant cataracts, and current research is being conducted to determine the protein's relation to a variety of other diseases and disorders, including variable zonular pulverulent cataract, coppock-like cataract, blindness, pneumonia, ADHD, bronchitis, and cancer. Gamma-crystallin C has been linked to eye development and visual perception, and interacts with proteins such as CRYAA, CRYBB2, CRYAB, and HSPB1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: gamma C Crystallin