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Gamma-crystallin C, or CRYGC for short, contains a 174 amino acid isoform that is 21 kDa, and is involved in supporting the eye lens through its highly symmetrical and organized gene cluster. Research has found that defects in the protein are a cause of autosomal dominant cataracts, and current research is being conducted to determine the protein's relation to a variety of other diseases and disorders, including variable zonular pulverulent cataract, coppock-like cataract, blindness, pneumonia, ADHD, bronchitis, and cancer. Gamma-crystallin C has been linked to eye development and visual perception, and interacts with proteins such as CRYAA, CRYBB2, CRYAB, and HSPB1.
