Galanin R2/GALR2 Antibody

Immunohistochemistry-Paraffin: Galanin R2/GALR2 Antibody [NLS4155] - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry-Paraffin: Galanin R2/GALR2 Antibody [NLS4155] - Analysis of anti-GALR2 antibody with human brain, neurons and glia.

Immunohistochemistry-Paraffin: Galanin R2/GALR2 Antibody [NLS4155] - Analysis of anti-GALR2 antibody with human brain, cerebellum.

Product Discontinued

Galanin R2/GALR2 Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from C-terminus of human GALR2.
• Localization: Integral membrane protein
• Specificity: Human GALR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except RBM14 (44%).
• Predicted Species: Primate (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GALR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Gibbon (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Galanin R2/GALR2 Antibody

• GAL2R
• GAL2-R
• Galanin R2
• galanin receptor 2
• galanin receptor type 2
• GalaninR2
• GALNR2
• GALNR2MGC125984
• GALR2
• GALR-2
• MGC125983

Background

GalR2 is a Galanin Receptor that is involved in neuroendocrine regulation and control of feeding behavior. In contrast to GalR1, the primary signaling mechanism of GalR2 is through phospholipase C/protein kinase C. GalR2 expression has been documented widely in the brain and in peripheral tissues including small intestine, heart, kidney, and liver. Localization data from rat CNS indicate high levels of expression in dorsal root ganglia, amygdala, Purkinje neurons, dentate gyrus, hypothalamus, pituitary, and cingulate, entorhinal, and piriform cortices, among others. Conflicting expression results have been documented in the literature with respect to the CNS and peripheral expression patterns. ESTs have been isolated from mouse brain libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALR2
• Entrez:
  • 8811(Human)
• Uniprot:
  • O43603()