Galanin R2/GALR2 Products

Antibodies
Galanin R2/GALR2 Antibody - B ...
Galanin R2/GALR2 Antibody - BSA Free
Species: Hu, Mu, Rt, Bv, Ha, Pm, Pm
Applications: IHC
Host: Rabbit Polyclonal
Galanin R2/GALR2 Antibody - B ...
Galanin R2/GALR2 Antibody - BSA Free
NBP1-91921
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
ELISA Kits
Rat Galanin R2/GALR2 ELISA Ki ...
Rat Galanin R2/GALR2 ELISA Kit (Co...
NBP2-76731
Species: Rt
Applications: ELISA
Proteins
Galanin R2/GALR2 Recombinant ...
Galanin R2/GALR2 Recombinant Prote...
NBP1-91921PEP
Species: Hu
Applications: AC

Description

Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Human
Product By Gene ID 8811
Alternate Names
  • GAL2-R
  • galanin receptor 2
  • galanin receptor type 2
  • GALNR2MGC125984
  • GALR-2
  • MGC125983

Research Areas for Galanin R2/GALR2

Find related products by research area and learn more about each of the different research areas below.

GPCR