G protein alpha Products

Antibodies
G protein alpha Antibody
G protein alpha Antibody
NBP1-31730
Species: Hu, Mu, Rt, Bovine, Canine, Porcine, Xenopus
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
G protein alpha Antibody
G protein alpha Antibody
NBP1-58349
Species: Hu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
G protein alpha Antibody
G protein alpha Antibody
NBP1-31405
Species: Hu, Mu, Bovine, Canine, Porcine, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
G protein alpha Overexpressio ...
G protein alpha Overexpression Lys...
NBL1-11160
Applications: WB
G protein alpha Overexpressio ...
G protein alpha Overexpression Lys...
NBP2-10677
Applications: WB
G protein alpha Overexpressio ...
G protein alpha Overexpression Lys...
NBP2-05782
Applications: WB
Proteins
G protein alpha Recombinant P ...
G protein alpha Recombinant Protein
H00002778-P01
Species: Hu
Applications: WB, ELISA, PA
G protein alpha Recombinant P ...
G protein alpha Recombinant Protei...
NBP1-89754PEP
Species: Hu
Applications: AC
G protein alpha Recombinant P ...
G protein alpha Recombinant Protei...
NBP1-89752PEP
Species: Hu
Applications: AC
RNAi
G protein alpha RNAi
G protein alpha RNAi
H00002778-R02
Species: Hu
Applications: RNAi, RNAi SP
G protein alpha RNAi
G protein alpha RNAi
H00002778-R03
Species: Hu
Applications: RNAi, RNAi SP
G protein alpha RNAi
G protein alpha RNAi
H00002778-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

G protein alpha has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contains a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 2778
Alternate Names
  • XLalphas
  • GNASXL
  • secretogranin VI
  • POH
  • protein ALEX
  • PHP1C
  • neuroendocrine secretory protein
  • PHP1B
  • guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
  • PHP1A
  • guanine nucleotide regulatory protein
  • AHO
  • GSP
  • Extra large alphas protein
  • Alternative gene product encoded by XL-exon
  • Adenylate cyclase-stimulating G alpha protein
  • NESP55
  • guanine nucleotide binding protein (G protein), alpha stimulating activitypolypeptide 1
  • MGC33735
  • NESP
  • GNAS1GSA
  • GPSAC20orf45
  • SCG6
  • GNAS complex locus

Research Areas for G protein alpha

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for G protein alpha

Learn more about PTMs related to G protein alpha.

Methylation
Phosphorylation
Reduction
Demethylation

Bioinformatics Tool for G protein alpha

Discover related pathways, diseases and genes to G protein alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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