FXYD5/Dysadherin Antibody (CL14037) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: IHC
• Clone: CL14037
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

FXYD5/Dysadherin Antibody (CL14037) [mFluor Violet 610 SE] Summary

• Immunogen: This antibody was generated using a recombinant protein sequence of Q96DB9, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FXYD5
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for FXYD5/Dysadherin Antibody (CL14037) [mFluor Violet 610 SE]

• DYSAD
• Dysadherin
• EF-8
• FXYD domain containing ion transport regulator 5
• FXYD domain-containing ion transport regulator 5
• FXYD5
• IWU1
• KCT1
• keratinocytes associated transmembrane protein 1
• OIT2
• PRO6241
• RIC

Background

Dysadherin encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FXYD5