Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | 462902 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Alexa Fluor 700 |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
Conjugate | Catalog # | Availability | Size | Price |
---|---|---|---|---|
Alexa Fluor 350 | IC40691U-100UG | |||
Alexa Fluor 405 | IC40691V-100UG | |||
Alexa Fluor 488 | IC40691G-100UG | |||
Alexa Fluor 594 | IC40691T-100UG | |||
Alexa Fluor 647 | IC40691R-100UG | |||
Alexa Fluor 750 | IC40691S-100UG | |||
Unconjugated | MAB40691 | |||
Immunogen | E. coli-derived recombinant human FRS2 Asn121-Asn449 Accession # Q8WU20 |
Specificity | Detects human FRS2 in direct ELISAs. |
Isotype | IgG2b |
Clonality | Monoclonal |
Host | Mouse |
Gene | FRS2 |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells. |
Storage | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Preservative | 0.09% Sodium Azide |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
FRS2 (FGFR substrate 2; also SNT and FSR2-alpha ) is a 70‑90 kDa member of the FSR family of lipid-anchored docking proteins. It is an intermediary between FGF and TRK receptors, and their Ras/MAPK signaling cascades. Human FRS2 is 512 amino acids (aa) in length. It contains a membrane-anchoring myristoylation signal (aa 1‑6), a PTB domain that interacts with FGF and NGF receptors (aa 13‑115), and a C-terminal Tyr-rich region that serves as a docking site for Grb2 and Shp2 (aa 196‑471). One splice form shows a deletion of the C-terminal four amino acids. Over aa 121‑449, human FRS2 is 99% and 94% aa identical to dog and mouse FRS2, respectively.
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | IC40691U | |
Alexa Fluor 405 | IC40691V | |
Alexa Fluor 488 | IC40691G | |
Alexa Fluor 594 | IC40691T | |
Alexa Fluor 647 | IC40691R | |
Alexa Fluor 700 | IC40691N | |
Alexa Fluor 750 | IC40691S |
Diseases for FRS2 Antibody (IC40691N)Discover more about diseases related to FRS2 Antibody (IC40691N).
| Pathways for FRS2 Antibody (IC40691N)View related products by pathway.
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PTMs for FRS2 Antibody (IC40691N)Learn more about PTMs related to FRS2 Antibody (IC40691N).
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