FLIP Antibody (NF6) - BSA Free

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clone: NF6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

FLIP Antibody (NF6) - BSA Free Summary

• Description: Novus Biologicals Mouse FLIP Antibody (NF6) - BSA Free (NBP2-80081) is a monoclonal antibody validated for use in IHC, WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human FLIP (aa 1-480).
• Specificity: Recognizes short (FLIPS) and long (FLIPL) splice variants of human FLIP. This antibody recognizes an epitope in the N-terminal DED region (aa1-194).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CFLAR
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot 1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 10% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for FLIP Antibody (NF6) - BSA Free

• CASHFADD-like antiapoptotic molecule 1
• CASP8 and FADD-like apoptosis regulator
• CASP8AP1
• Caspase homolog
• Caspase-eight-related protein
• Caspase-like apoptosis regulatory protein
• caspase-related inducer of apoptosis
• CASPER
• CasperFLAME1
• Cellular FLICE-like inhibitory protein
• CFLAR
• c-FLIPR
• c-FLIPS
• CLARPMACH-related inducer of toxicity
• FADD-like apoptotic molecule
• FLAME
• FLAME-1
• FLIP
• I-FLICE
• I-FLICEMRITc-FLIPFLIPc-FLIPL
• Inhibitor of FLICE
• usurpin beta
• Usurpin

Background

Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CFLAR