FLIP Products

Antibodies
FLIP Antibody
FLIP Antibody
NBP1-77020
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
FLIP Antibody
FLIP Antibody
NB100-56141
Species: Hu
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
FLIP Antibody (2F12)
FLIP Antibody (2F12)
H00008837-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P
Host: Mouse Monoclonal
Antibody Pairs
FLIP Antibody Pair
FLIP Antibody Pair
H00008837-PW1
Species: Hu
Applications: WB, IP
FLIP Antibody Pair
FLIP Antibody Pair
H00008837-PW2
Species: Hu
Applications: WB, IP
FLIP Antibody Pair
FLIP Antibody Pair
DI0078
Species: Hu
Applications: PLA
Lysates
FLIP Overexpression Lysate (D ...
FLIP Overexpression Lysate (Denatu...
H00008837-T01
Species: Hu
Applications: WB
FLIP Overexpression Lysate (N ...
FLIP Overexpression Lysate (Native)
NBL1-09128
Applications: WB
FLIP Overexpression Lysate (N ...
FLIP Overexpression Lysate (Native)
NBP2-11391
Applications: WB
Proteins
Recombinant Human FLIP Protei ...
Recombinant Human FLIP Protein
NBP1-72439
Species: Hu
Applications: PAGE
FLIP Recombinant Protein Anti ...
FLIP Recombinant Protein Antigen
NBP1-85675PEP
Species: Hu
Applications: AC
FLIP Blocking Peptide
FLIP Blocking Peptide
NBP1-77016PEP
Species: Hu
Applications: AC
RNAi
FLIP RNAi
FLIP RNAi
H00008837-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 8837
Alternate Names
  • CASPER
  • CASP8AP1
  • Usurpin
  • Inhibitor of FLICE
  • usurpin beta
  • Cellular FLICE-like inhibitory protein
  • FADD-like apoptotic molecule
  • Caspase-like apoptosis regulatory protein
  • caspase-related inducer of apoptosis
  • Caspase-eight-related protein
  • c-FLIPS
  • Caspase homolog
  • c-FLIPR
  • FLAME
  • I-FLICEMRITc-FLIPFLIPc-FLIPL
  • CasperFLAME1
  • CLARPMACH-related inducer of toxicity
  • CASHFADD-like antiapoptotic molecule 1
  • FLAME-1
  • CASP8 and FADD-like apoptosis regulator

Research Areas for FLIP

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology
Signal Transduction
Tumor Suppressors

Bioinformatics Tool for FLIP

Discover related pathways, diseases and genes to FLIP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related FLIP Blog Posts

Check out the latest blog posts on FLIP.
TRAIL-R2: The Trail Less Traveled
Cells undergo apoptotic programmed cell death in response to various stimuli, and this key mechanism is necessary for cellular morphogenesis, tissue homeostasis, and host defense. Particular cytokines such as tumor necrosis factor (TNF) and the Fas li...    Read more.
Read more FLIP related blogs.