Fibronectin Antibody

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Immunohistochemistry-Paraffin: Fibronectin Antibody [NB110-41562] - Formalin fixed paraffin embedded human kidney stained with Fibronectin antibody.(NB110-41562)
Immunohistochemistry-Paraffin: Fibronectin Antibody [NB110-41562] - Formalin fixed paraffin embedded human kidney stained with Fibronectin antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Fibronectin Antibody Summary

Description
Novus Biologicals Rabbit Fibronectin Antibody (NB110-41562) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Fibronectin isolated from a pool of normal human plasma.
Localization
Basement membrane, connective tissue
Marker
Mesenchymal Cells Marker
Specificity
This reacts with human fibronectin in liver, tonsil, skin and kidney. Traces of contaminating antibodies have been removed by solid-phase absorption. Only the fibronectin arch was observed in crossed immunoelectrophoresis.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FN1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Frozen 1:50-1:250
  • Immunohistochemistry-Paraffin
Application Notes
IHC-P: recommended pretreatment of EDTA buffer, pH 8.0. Recommended incubation time of 30 min at RT.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4), 0.2% BSA, Tween-20
Preservative
0.05% Sodium Azide
Purity
Affinity purified

Alternate Names for Fibronectin Antibody

  • CIG
  • ED-B
  • fibronectin 1
  • Fibronectin
  • FINC
  • FN
  • FN1
  • FNZ
  • GFND
  • GFND2
  • LETS
  • MSF
  • SMDCF

Background

Fibronectin is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. They occur as dimers of two 250 kDa subunits. They have binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumours.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Fibronectin Antibody (NB110-41562) (0)

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Secondary Antibodies

 

Isotype Controls

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Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...  Read full blog post.

Fibronectin: Organizing Cell Activity across the ECM
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Using the Laminin Antibody in Angiogenesis Research
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Bioinformatics

Gene Symbol FN1
Entrez