Fibromodulin/FMOD Antibody (549302) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 549302
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Fibromodulin/FMOD Antibody (549302) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Fibromodulin/FMOD
  Asp75-Ile376
  Accession # NP_002014
• Specificity: Detects human Fibromodulin/FMOD in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Lumican is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Fibromodulin/FMOD Antibody (549302) [Alexa Fluor® 488]

• Collagen-binding 59 kDa protein
• fibromodulin proteoglycan
• Fibromodulin
• FM
• FMOD
• Keratan sulfate proteoglycan fibromodulin
• SLRR2E
• SLRR2EKSPG fibromodulin

Background

Fibromodulin (FMOD) is a Class II small leucine-rich proteoglycan (SLRP) superfamily member. The ~50‑70 kDa protein contains a sulfated N‑terminal complement C1q binding domain (aa 19‑98) and 12 leucine-rich repeats (aa 75‑376). A 40 kDa form is reported in dental tissues. It participates in collagen fibrillogenesis in many tissues and competes with Lumican for collagen binding. It can participate in inflammation by activating complement. In epidermal keratinocytes, it may be located in the cytoplasm. The region of human FMOD used as an immunogen shares 96% aa identity with mouse or rat FMOD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.