Immunocytochemistry/ Immunofluorescence: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Analysis of Fibrillin-1 (green) showing staining in the cytoplasm of SH-SY5Y cells (right) compared to a negative control without ...read more
Immunohistochemistry-Frozen: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Adult eye (blue) and muscle (red) tissue. An image was captured using epifluorescent microscope detecting signals from Alexa fluor 568 ...read more
Immunocytochemistry/ Immunofluorescence: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Analysis of Fibrillin-1 (green) showing staining in the cytoplasm of A431 cells (right) compared to a negative control without ...read more
Porcine reactivity reported in scientific literature (PMID: 17599682).
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4) and 0.2% BSA
0.09% Sodium Azide
Protein G purified
Alternate Names for Fibrillin 1 Antibody (11C1.3)
fibrillin 1 (Marfan syndrome)
Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for Fibrillin 1 Antibody (NB110-8146). (Showing 1 - 1 of 1 FAQs).
Hi - I have been looking at the fibrillin1 antibodies on your website. You indicate that some may be suitable for canine tissue on the front page http://www.novusbio.com/primary-antibodies/fibrillin-1. could you let me know which of the 10 antibodies is the most suitable for canine.
We have unfortuantely not tested any of our products in canine samples. If you would like to try one of our product with canine samples, you would qualify for our Innovator's Reward Program. In exchange for a review of our product in an untested application or species, we would issue you a credit voucher for the purchase price. If you would like us to check the homology of a certain product against the canine sequence, just contact our technical support department at firstname.lastname@example.org.
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