Fibrillin 1 Antibody (11C1.3)

Images

 
Immunocytochemistry/ Immunofluorescence: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Analysis of Fibrillin-1 (green) showing staining in the cytoplasm of SH-SY5Y cells (right) compared to a negative control without ...read more
Immunohistochemistry-Frozen: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Adult eye (blue) and muscle (red) tissue. An image was captured using epifluorescent microscope detecting signals from Alexa fluor 568 ...read more
Immunocytochemistry/ Immunofluorescence: Fibrillin 1 Antibody (11C1.3) [NB110-8146] - Analysis of Fibrillin-1 (green) showing staining in the cytoplasm of A431 cells (right) compared to a negative control without ...read more

Product Details

Summary
Reactivity Hu, Po, Bv, FeSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-Fr, IHC-P, IM
Clone
11C1.3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

Fibrillin 1 Antibody (11C1.3) Summary

Immunogen
Microfibrils from zonular apparatus of bovine eye
Epitope
Amino acids 451 - 909.
Localization
Extracellular microfibrils.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FBN1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 - 2 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:100
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Frozen 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Immunomicroscopy 1:10 - 1:500
Reviewed Applications
Read 1 Review rated 4
using
NB110-8146 in the following applications:

Publications
Read Publications using
NB110-8146 in the following applications:

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID: 17599682).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein G purified

Alternate Names for Fibrillin 1 Antibody (11C1.3)

  • ACMICD
  • Asprosin
  • FBN
  • FBN1
  • fibrillin 1 (Marfan syndrome)
  • Fibrillin 1
  • fibrillin 15
  • fibrillin-1
  • GPHYSD2
  • MASS
  • MFS1
  • OCTD
  • SGS
  • SSKS
  • WMS
  • WMS2

Background

Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Fibrillin 1 Antibody (NB110-8146)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-Fr.


Filter By Application
IHC-Fr
(2)
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Filter By Species
Human
(1)
All Species

Review for Fibrillin 1 Antibody (NB110-8146) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Feline.

Reviews using NB110-8146:
Filter by Applications
IHC-Fr
(1)
All Applications
Filter by Species
Feline
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen Fibrillin 1 NB110-8146
Enlarge
reviewed by:
Anonymous
IHC-Fr Feline 06/05/2018
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedAdult eye and muscle tissue (labeled E and M, respectively)
SpeciesFeline
LotTE2577931A

Comments

CommentsUsed at 1:100 dilution

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Fibrillin 1 Antibody (NB110-8146). (Showing 1 - 1 of 1 FAQs).

  1. Hi - I have been looking at the fibrillin1 antibodies on your website. You indicate that some may be suitable for canine tissue on the front page http://www.novusbio.com/primary-antibodies/fibrillin-1. could you let me know which of the 10 antibodies is the most suitable for canine.
    • We have unfortuantely not tested any of our products in canine samples. If you would like to try one of our product with canine samples, you would qualify for our Innovator's Reward Program. In exchange for a review of our product in an untested application or species, we would issue you a credit voucher for the purchase price. If you would like us to check the homology of a certain product against the canine sequence, just contact our technical support department at technical@novusbio.com.

Secondary Antibodies

 

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Anonymous
06/05/2018
Application: IHC-Fr
Species: Feline

Bioinformatics

Gene Symbol FBN1
Entrez
Uniprot