Fetal Hemoglobin Antibody - BSA Free Summary
| Description |
Novus Biologicals Sheep Fetal Hemoglobin Antibody - BSA Free (NBP3-14755) is a polyclonal antibody validated for use in Immunoelectrophoresis. All Novus Biologicals antibodies are covered by our 100% guarantee. |
| Immunogen |
no immunogen data |
| Clonality |
Polyclonal |
| Host |
Sheep |
| Gene |
HBG1 |
| Purity |
Multi-step |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunoelectrophoresis Neat
|
Packaging, Storage & Formulations
| Storage |
Store at 2 - 8 C / 1 year from date of receipt |
| Buffer |
Phosphate Buffered Saline (PBS) containing |
| Preservative |
0.09% Sodium Azide |
| Purity |
Multi-step |
Alternate Names for Fetal Hemoglobin Antibody - BSA Free
Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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