FCRLA/FCRLM1 Antibody (865910) [DyLight 680]

• Reactivity: Mu
• Applications: WB, Flow, CyTOF-ready
• Clone: 865910
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 680

FCRLA/FCRLM1 Antibody (865910) [DyLight 680] Summary

• Immunogen: E. coli-derived recombinant mouse FCRLA
  Lys221-Lys352
  Accession # Q920A9
• Specificity: Detects mouse FCRLA in ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: FCRLA
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for FCRLA/FCRLM1 Antibody (865910) [DyLight 680]

• Fc receptor homolog expressed in B cells (FREB)
• Fc receptor homolog expressed in B-cells
• Fc receptor related protein X
• Fc receptor-like A
• Fc receptor-like and mucin-like 1
• Fc receptor-related protein X
• FCRL1
• FCRLA
• FCRLb
• FCRLc1
• FCRLc2
• FCRLd
• FCRLe
• FCRLFc receptor-like protein
• FCRLM1
• FCRLX
• FcRX
• FREB
• FREBFc receptor-like and mucin-like protein 1
• MGC4595

Background

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRLA