FCRLA/FCRLM1 Antibody (865910) [Alexa Fluor® 532]

• Reactivity: Mu
• Applications: WB, Flow, CyTOF-ready
• Clone: 865910
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 532

FCRLA/FCRLM1 Antibody (865910) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant mouse FCRLA
  Lys221-Lys352
  Accession # Q920A9
• Specificity: Detects mouse FCRLA in ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: FCRLA
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for FCRLA/FCRLM1 Antibody (865910) [Alexa Fluor® 532]

• Fc receptor homolog expressed in B cells (FREB)
• Fc receptor homolog expressed in B-cells
• Fc receptor related protein X
• Fc receptor-like A
• Fc receptor-like and mucin-like 1
• Fc receptor-related protein X
• FCRL1
• FCRLA
• FCRLb
• FCRLc1
• FCRLc2
• FCRLd
• FCRLe
• FCRLFc receptor-like protein
• FCRLM1
• FCRLX
• FcRX
• FREB
• FREBFc receptor-like and mucin-like protein 1
• MGC4595

Background

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRLA