Western blot shows lysates of RPMI 8226 human multiple myeloma cell line and K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human FCRL4/FcRH4 Antigen ...read more
Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4 Gln16-Asp385 Accession # Q96PJ5
Detects human FCRL4/FcRH4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross‑reactivity with recombinant human (rh) IRTA2, rhIRTA3, rhIRTA4, and rhIRTA5 is observed.
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FcRH4, also known as IRTA1 (immunoglobulin superfamily receptor translocation associated 1), is a member of the Ig superfamily. It shares sequence homology with the classical Fc receptors. FcRH4 is preferentially expressed in B cells and contains three potential ITIM motifs in its extracellular domain. The gene for FcRH4 is localized to the human chromosome Iq 21‑23 region, a hotspot for translocation events.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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