Species: Mu
Applications: WB, Flow, CyTOF-ready
Host: Rat Monoclonal
Species: Mu
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: WB, PAGE
Species: Hu
Applications: WB, ELISA, MA, AP
Description
Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human Human |
| Product By Gene ID |
84824 |
| Alternate Names |
- Fc receptor homolog expressed in B cells (FREB)
- Fc receptor homolog expressed in B-cells
- Fc receptor related protein X
- Fc receptor-like A
- Fc receptor-like and mucin-like 1
- Fc receptor-related protein X
- FCRL1
- FCRLa
- FCRLb
- FCRLc1
- FCRLc2
- FCRLd
- FCRLe
- FCRLFc receptor-like protein
- FCRLM1
- FCRLX
- FCRX
- FcRX
- FREBFc receptor-like and mucin-like protein 1
- MGC4595
|