FCRLA/FCRLM1 Products

Description

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]

Bioinformatics

Entrez	84824 Human
Uniprot	NM_032738 Human NP_116127.3 Human Q7L513 Human
Product By Gene ID	84824
Alternate Names	Fc receptor homolog expressed in B cells (FREB) Fc receptor homolog expressed in B-cells Fc receptor related protein X Fc receptor-like A Fc receptor-like and mucin-like 1 Fc receptor-related protein X FCRL1 FCRLa FCRLb FCRLc1 FCRLc2 FCRLd FCRLe FCRLFc receptor-like protein FCRLM1 FCRLX FCRX FcRX FREBFc receptor-like and mucin-like protein 1 MGC4595