FCRLA/FCRLM1 Antibody (865910) [CoraFluor™ 1]

• Reactivity: Mu
• Applications: WB, Flow, CyTOF-ready
• Clone: 865910
• Clonality: Monoclonal
• Host: Rat
• Conjugate: CoraFluor 1

FCRLA/FCRLM1 Antibody (865910) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: E. coli-derived recombinant mouse FCRLA
  Lys221-Lys352
  Accession # Q920A9
• Specificity: Detects mouse FCRLA in ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: FCRLA
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for FCRLA/FCRLM1 Antibody (865910) [CoraFluor™ 1]

• Fc receptor homolog expressed in B cells (FREB)
• Fc receptor homolog expressed in B-cells
• Fc receptor related protein X
• Fc receptor-like A
• Fc receptor-like and mucin-like 1
• Fc receptor-related protein X
• FCRL1
• FCRLA
• FCRLb
• FCRLc1
• FCRLc2
• FCRLd
• FCRLe
• FCRLFc receptor-like protein
• FCRLM1
• FCRLX
• FcRX
• FREB
• FREBFc receptor-like and mucin-like protein 1
• MGC4595

Background

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRLA