Fc gamma RIIB/C (CD32b/c) Antibody (190710)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA(Cap)
Clone
190710
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Formulation Size Price

Fc gamma RIIB/C (CD32b/c) Antibody (190710) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Fc gamma RIIB/C
Ala46-Pro217
Accession # P31994
Specificity
Detects human Fc gamma RIIB/C in ELISAs. In a sandwich ELISA shows approximately 40% cross-reactivity with recombinant human (rh) Fc gamma  RIIA and no cross‑reactivity with rhFc gamma RI, rmFc gamma RI, rmFc gamma  RIIB, rhFc gamma RIIIB, rmFc gamma RIII, or rmFcrl3/CD16-2.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
FCGR2B
Purity
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.5-2.0 ug/mL
  • ELISA Standard (Matched Pair)
Application Notes
ELISA Capture: Human Fc gamma RIIB/C (CD32b/c) Antibody (Catalog # MAB18751)
ELISA Detection: Human Fc gamma RIIB/C (CD32b/c) Biotinylated Antibody (Catalog # BAM1875)
Standard: Recombinant Human Fc gamma RIIB/C (CD32b/c) (Catalog # 1875-CD)
Publications
Read Publication using
MAB18751 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Fc gamma RIIB/C (CD32b/c) Antibody (190710)

  • Fc gamma RIIB/C (CD32b/c)

Background

Fc gamma RII, also known as CD32, is a group of three closely related proteins (Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIC) that share greater than 94% amino acid identity in their extracellular domains with Fc gamma RIIB and Fc gamma RIIC having identical extracellular domains. They function as transmembrane receptors for the Fc portion of IgG molecules. These proteins are expressed by various hematopoietic cells including monocytes, macrophages, neutrophils, NK, T and B cells. The Fc gamma RII proteins are involved in phagocytosis of immune complexes and modulation of antibody production by B cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Fc gamma RIIB/C (CD32b/c) Antibody (MAB18751)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Human
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Bioinformatics

Gene Symbol FCGR2B
Uniprot