FANCB Antibody - BSA Free

Immunoprecipitation: FANCB Antibody [NBP1-19087] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-FANCB antibody used for IP at 10 ug/mg lysate. FANCB was also immunoprecipitated by rabbit anti-FANCB antibody NBP1-19086, which recognizes an upstream epitope.

• Reactivity: Hu
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

FANCB Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit FANCB Antibody - BSA Free (NBP1-19087) is a polyclonal antibody validated for use in IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 820 and 859 of human Fanconi anemia complementation group B using the numbering given in entry NP_001018123.1 (GeneID 2187).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FANCB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 10 ug/mg lysate
• Application Notes: This antibody is not recommended for Western Blot analysis.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for FANCB Antibody - BSA Free

• EC 2.8.1
• EC 3.6.3.14
• FA2
• FAAP90
• FAAP95FAB
• FACB
• Fanconi anemia group B protein
• Fanconi anemia, complementation group B
• Fanconi anemia-associated polypeptide of 95 kDa
• FLJ34064
• Protein FACB

Background

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FANCB
• Entrez:
  • 2187(Human)
• Uniprot:
  • NP_001018123.1(Human)