Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Host: Mouse Polyclonal
Applications: WB, ELISA, PA, PAGE, AP
Applications: WB, ELISA, PA, AP
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq]
|Product By Gene ID
- EC 18.104.22.168
- EC 2.8.1
- Protein FACB
- Fanconi anemia-associated polypeptide of 95 kDa
- Fanconi anemia group B protein
- Fanconi anemia, complementation group B
Bioinformatics Tool for FANCB
Discover related pathways, diseases and genes to FANCB. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related FANCB Blog Posts
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|Fanconi Antibodies and Cancer Research
We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)... Read more.