EWSR1 Antibody - BSA Free

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-EWSR1)

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Chicken
• Conjugate: Unconjugated
• Format: BSA Free

EWSR1 Antibody - BSA Free Summary

• Immunogen: The immunogen for this antibody was a sequence from 380a.a. to 448a.a. from RNA-binding protein EWSR1(a 656a.a. long protein)
• Localization: Cell surface, Cytoplasmic and Nuclear. Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation.
• Specificity: RNA-binding protein EWSR1
• Clonality: Polyclonal
• Host: Chicken
• Gene: EWSR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Anti-EWSR1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
• Control:

  EWSR1 Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for EWSR1 Antibody - BSA Free

• bK984G1.4
• Ewing sarcoma breakpoint region 1 protein
• Ewing sarcoma breakpoint region 1
• Ewings sarcoma EWS-Fli1 (type 1) oncogene
• EWS oncogene
• EWS
• EWSR1
• EWSRNA-binding protein EWS

Background

Might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking. or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EWSR1
• Entrez:
  • 2130(Human)
  • 14030(Mouse)
  • 289752(Rat)
• Uniprot:
  • Q01844(Human)