ERR gamma/NR3B3 Products

Antibodies
ERR gamma/NR3B3 Antibody (H68 ...
ERR gamma/NR3B3 Antibody (H6812)
PP-H6812-00
Species: Hu
Applications: WB, IHC, IP, DirELISA
Host: Mouse Monoclonal
ERR gamma/NR3B3 Antibody (1E5 ...
ERR gamma/NR3B3 Antibody (1E5)
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
ERR gamma/NR3B3 Antibody
ERR gamma/NR3B3 Antibody
NBP1-32853
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Antibody Pairs
ERR gamma/NR3B3 Antibody Pair ...
ERR gamma/NR3B3 Antibody Pair
H00002104-PW2
Species: Hu
Applications: WB, IP
Lysates
ERR gamma/NR3B3 Overexpressio ...
ERR gamma/NR3B3 Overexpression Lys...
NBL1-10347
Applications: WB
ERR gamma/NR3B3 Overexpressio ...
ERR gamma/NR3B3 Overexpression Lys...
NBP2-04535
Applications: WB
ERR gamma/NR3B3 Overexpressio ...
ERR gamma/NR3B3 Overexpression Lys...
H00002104-T01
Species: Hu
Applications: WB
Proteins
ERR gamma/NR3B3 Recombinant P ...
ERR gamma/NR3B3 Recombinant Protein
H00002104-P01
Species: Hu
Applications: WB, ELISA, PA
ERR gamma/NR3B3 Recombinant P ...
ERR gamma/NR3B3 Recombinant Protein
H00002104-P02
Species: Hu
Applications: WB, ELISA, PA
ERR gamma/NR3B3 Recombinant P ...
ERR gamma/NR3B3 Recombinant Protei...
NBP1-91873PEP
Species: Hu
Applications: AC
RNAi
ERR gamma/NR3B3 RNAi
ERR gamma/NR3B3 RNAi
H00002104-R03
Species: Hu
Applications: RNAi, RNAi SP
ERR gamma/NR3B3 RNAi
ERR gamma/NR3B3 RNAi
H00002104-R02
Species: Hu
Applications: RNAi, RNAi SP
ERR gamma/NR3B3 RNAi
ERR gamma/NR3B3 RNAi
H00002104-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Estrogen related receptor (ERR gamma), a NR3 Steroid Receptor is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members (1,2, and 3) share an almost identical DNA binding domain, which has 68% amino acid identity with that of estrogen receptor. Studies involving the crystal structure of the LBD have shown a complex between ERR3 and SRC1. ERR gamma has been suggested to affect differentiation of the brain, heart, and kidney. ERR gamma binds as a monomer to an extended half site of the ERRE type (TCAAGGTCA). ERR gamma has been shown to interact with PGC1 alpha and has been implicated in the regulation of mitochondrial energy metabolism. In humans, ERR gamma pre mRNA undergoes extensive alternative splicing at the 5 prime end, yielding at least six mRNA splice variants and two protein isoforms that differ by 23 amino acids in the N terminus. ERR gamma has been shown to be overexpressed in breast tumors, and its expression is correlated with levels of ErbB4, a likely indicator of preferred clinical course. As a result, ERR gamma has been suggested to be a potential biomarker for favorable clinical course and, possibly, hormonal sensitivity, and as a candidate target for therapeutic development.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 2104
Alternate Names
  • ERRG2
  • FLJ16023
  • ERRgamma
  • DKFZp781L1617
  • ERR gamma-2
  • NR3B3
  • KIAA0832
  • ERR3
  • Nuclear receptor subfamily 3 group B member 3
  • Estrogen receptor-related protein 3
  • estrogen-related receptor gamma

Research Areas for ERR gamma/NR3B3

Find related products by research area and learn more about each of the different research areas below.

GPCR

PTMs for ERR gamma/NR3B3

Learn more about PTMs related to ERR gamma/NR3B3.

Oxidation
Phosphorylation
Acetylation
Dephosphorylation
Sumoylation
Reduction
Ubiquitination

Bioinformatics Tool for ERR gamma/NR3B3

Discover related pathways, diseases and genes to ERR gamma/NR3B3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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