EphA4 Antibody

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Immunohistochemistry-Paraffin: EphA4 Antibody [NB110-39005] - Analysis of anti-EPHA4 antibody with human glomerulus at concentration 18 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bt, Bv, Ca, Eq, Ha, Mk, Pm, Rb, Ch, Op, TrSpecies Glossary
Applications ELISA, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

EphA4 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from C-terminus of human EPHA4.
Epitope
C-terminal domain of human
Specificity
Human EPHA4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Turkey (90%), Chicken (90%), Opossum (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EPHA4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 18 ug/ml.

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Platypus (95%), Lizard (95%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EphA4 Antibody

  • Cek8
  • EC 2.7.10
  • EC 2.7.10.1
  • EK8
  • EPH receptor A4
  • EphA4
  • EPH-like kinase 8
  • ephrin type-A receptor 4
  • Hek8
  • receptor protein-tyrosine kinase HEK8
  • SEK
  • Sek1
  • TYRO1 protein tyrosine kinase
  • Tyro1
  • Tyrosine-protein kinase receptor SEK
  • Tyrosine-protein kinase TYRO1

Background

Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5 but binds more poorly to ephrin-A2 and -A3. Eph receptor A4 may play a role in a signal transduction process involved in hindbrain pattern formation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EPHA4
Entrez