EphA4 Antibody - BSA Free

Immunohistochemistry-Paraffin: EphA4 Antibody - BSA Free [NB110-39005] - Analysis of anti-EPHA4 antibody with human glomerulus at concentration 18 ug/ml.

• Reactivity: Hu, Mu, Rt, Po, Bt, Bv, Ca, Eq, Ha, Pm, Pm, Rb, Ma-Op
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

EphA4 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 20 amino acid peptide from C-terminus of human EphA4.
• Epitope: C-terminal domain of human
• Specificity: Human EPHA4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Opossum (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EPHA4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 18 ug/ml.
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for EphA4 Antibody - BSA Free

• Cek8
• EC 2.7.10
• EC 2.7.10.1
• EK8
• EPH receptor A4
• EphA4
• EPH-like kinase 8
• ephrin type-A receptor 4
• Hek8
• receptor protein-tyrosine kinase HEK8
• SEK
• Sek1
• TYRO1 protein tyrosine kinase
• Tyro1
• Tyrosine-protein kinase receptor SEK
• Tyrosine-protein kinase TYRO1

Background

Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5 but binds more poorly to ephrin-A2 and -A3. Eph receptor A4 may play a role in a signal transduction process involved in hindbrain pattern formation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EPHA4
• Entrez:
  • 2043(Human)