ENPP-3/CD203c Antibody (NP4D6) [Allophycocyanin/Cy7]

• Reactivity: Hu
• Applications: Flow, ICC/IF, CyTOF-ready
• Clone: NP4D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

ENPP-3/CD203c Antibody (NP4D6) [Allophycocyanin/Cy7] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Additional Information: Clone NP4D6 was used by HLDA to establish CD designation.
• Immunogen: HEK-293 cells transfected with human CD203c
• Specificity: The mouse monoclonal antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation. HLDA VIII
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ENPP3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Cy is a registered trademark of Global Life Sciences Solutions Germany GmbH.

Alternate Names for ENPP-3/CD203c Antibody (NP4D6) [Allophycocyanin/Cy7]

• B10
• CD203c antigen
• CD203c
• dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)
• dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)
• ectonucleotide pyrophosphatase/phosphodiesterase 3
• ectonucleotide pyrophosphatase/phosphodiesterase family member 3
• E-NPP 3
• ENPP3
• ENPP-3
• gp130RB13-6
• NPP3
• PD-IBETA
• PDNP3
• PDNP3B10
• Phosphodiesterase I beta
• Phosphodiesterase I/nucleotide pyrophosphatase 3
• phosphodiesterase-I beta

Background

The ENPP3 gene encodes a 875 amino acid long, 100 kDA ectonucleotide pyrophosphatase/phosphodiesterase family member 3 protein that separates multiple phosphodiester and phosphosulfate bonds, specifically in deoxynucleotides, nucleotide sugars, and NAD. ENPP3 participates in NAD metabolism, purine metabolism, riboflavin metabolism, and pantothenate and CoA biosynthesis. ENPP3 has been linked to carcinoma, bile duct cancer, urticaria, retinitis, epididymitis, prostatitis, urticaria, and asthma as it interacts with genes GRB2, CD38, NADK, BST1, and ACPP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ENPP3