EMMPRIN/CD147 Antibody (MEM-M6/2) [FITC]

Images

 
Flow Cytometry: EMMPRIN/CD147 Antibody (MEM-M6/2) [FITC] [NBP1-44585] - Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) FITC.
Flow Cytometry: EMMPRIN/CD147 Antibody (MEM-M6/2) [FITC] [NBP1-44585] - Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) biotin.

Product Details

Summary
Reactivity Hu, PoSpecies Glossary
Applications Flow
Clone
MEM-M6/2
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

EMMPRIN/CD147 Antibody (MEM-M6/2) [FITC] Summary

Immunogen
A soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the entire extracellular region of CD147 fused to the DNA coding for the hinge region, CH2 and CH3 domain of human IgG1.
Epitope
This antibody recognises extracellular Ig domain D1 of CD147 antigen.
Localization
Cell Membrane
Specificity
The antibody MEM-M6/2 recognizes extracellular Ig domain D1 of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
BSG
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 ug/ml
Application Notes
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Purity
Protein A purified

Notes

Store in the dark. Avoid prolonged exposure to light.

Alternate Names for EMMPRIN/CD147 Antibody (MEM-M6/2) [FITC]

  • 5F7
  • basigin (Ok blood group)
  • Basigin
  • BSG
  • CD147 antigen
  • CD147
  • Collagenase stimulatory factor
  • EMMPRIN
  • EMMPRINTCSF
  • Extracellular matrix metalloproteinase inducer
  • Leukocyte activation antigen M6
  • M6
  • OK blood group antigen
  • OK
  • Tumor cell-derived collagenase stimulatory factor

Background

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BSG
Entrez