WB, Simple Western, IHCHost:
WB, ELISA, Flow, IHC, IHC-P, IP, CyTOF-readyHost:
WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-readyHost:
Applications: WB, IP
WB, B/N, ELISA, PA
Applications: WB, ELISA, PA
CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.
Research Areas for EMMPRIN/CD147
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Bioinformatics Tool for EMMPRIN/CD147
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