ELOVL4 Antibody

Immunohistochemistry-Paraffin: ELOVL4 Antibody [NBP3-12303] - Human skin. 1:100 dilution in IHC blockign buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnfication.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

ELOVL4 Antibody Summary

• Description: Novus Biologicals Rabbit ELOVL4 Antibody (NBP3-12303) is a polyclonal antibody validated for use in IHC, WB, ELISA and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide corresponding to internal sequence amino acids 107-121 of Human ELOVL4. Sequence: SYICQSVDYSNNVHE
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ELOVL4
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 1:200
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ELOVL4 Antibody

• ADMD
• cancer/testis antigen 118
• CT118
• EC 2.3.1.n8
• elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
• elongation of very long chain fatty acids protein 4
• FLJ17667
• FLJ92876,3-keto acyl-CoA synthase ELOVL4
• Stargardt disease 3 (autosomal dominant)
• STGD2
• STGD3

Background

Mutations in ELOVL4, a 38-39 kDa protein photoreceptor cell-specific protein involved in the elongation of very long chain fatty acids, are linked with Stargardt-like macular dystrophy (STGD3), autosomal dominant macular dystrophy, and other pattern dystrophy. The ELOVL4 gene is homologous to mammalian and yeast enzymes involved in the membrane-bound fatty acid chain elongation system. It has been suggested that alterations in the biosynthesis of fatty acids may be implicated in the pathogenesis of inherited macular degeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ELOVL4