Elongin A Antibody

Images

 
Western Blot: Elongin A Antibody [NB100-40834] - Detection of Human TCEB3 on HeLa whole cell lysate using NB100-40834. TCEB3 was also immunoprecipitated by rabbit anti-TCEB3 antibodies NB100-40835 and NB100-40836.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

Elongin A Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 325 and 375 of human Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, elongin A) using the numbering given in entry NP_003189.1 (GeneID 6924).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TCEB3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Elongin A Antibody

  • EloA
  • Elongin 110 kDa subunit
  • elongin-A
  • FLJ38760
  • FLJ42849
  • RNA polymerase II transcription factor SIII subunit A1
  • SIII p110
  • SIII
  • TCEB3A
  • transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A)
  • transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
  • transcription elongation factor B alpha subunit
  • transcription elongation factor B polypeptide 3

Background

TCEB3 (Elongin A) is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TCEB3
Entrez
Uniprot