Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Description
TCEB3 (Elongin A) is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
6924 |
| Alternate Names |
- EloA
- Elongin 110 kDa subunit
- elongin-A
- Elongin-A
- FLJ38760
- FLJ42849
- RNA polymerase II transcription factor SIII subunit A1
- SIII p110
- SIII
- TCEB3A
- transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A)
- transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
- transcription elongation factor B alpha subunit
- transcription elongation factor B polypeptide 3
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