E-Selectin/CD62E Antibody (BBIG-E6 (13D5)) [Alexa Fluor® 488]

• Applications: Flow, IP, B/N, CyTOF-ready, ICC/IF
• Clone: BBIG-E6 (13D5)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

E-Selectin/CD62E Antibody (BBIG-E6 (13D5)) [Alexa Fluor® 488] Summary

• Immunogen: Activated HUVEC human umbilical vein endothelial cells
• Specificity: Detects human E‑Selectin/P‑Selectin (CD62E/P). Binds to COS cells transfected with human E-Selectin or human P-Selectin. It does not bind to CHO cells transfected with human ICAM-1, L-Selectin, PECAM-1 or VCAM-1.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

E-Selectin and P-Selectin are related (44% amino acid sequence identity) adhesion molecules containing multiple short complement-like repeats and an N-terminal C‑type lectin domain in their extracellular regions. E-Selectin is expressed on activated vascular endothelial cells and P-Selectin occurs on activated platelets and endothelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.