Dynactin Subunit 2/DCTN2/DCTN-50 Antibody

Images

 
Western Blot: Dynactin Subunit 2/DCTN2/DCTN-50 Antibody [NBP2-16115] - MCF-7.
Immunocytochemistry/ Immunofluorescence: Dynactin Subunit 2/DCTN2/DCTN-50 Antibody [NBP2-16115] - Analysis of methanol-fixed MCF-7.
Immunohistochemistry-Paraffin: Dynactin Subunit 2/DCTN2/DCTN-50 Antibody [NBP2-16115] - Breast ca.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Dynactin Subunit 2/DCTN2/DCTN-50 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human DCTN2. The exact sequence is proprietary.
Localization
Cytoplasm; cytoskeleton; Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DCTN2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP2-16115.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Dynactin Subunit 2/DCTN2/DCTN-50 Antibody

  • DCTN2
  • DCTN-50
  • DCTN5050 kD dynein-associated polypeptide
  • dynactin 2 (p50)
  • dynactin complex 50 kD subunit
  • Dynactin complex 50 kDa subunit
  • Dynactin Subunit 2
  • dynactin subunit 2,50 kDa dynein-associated polypeptide
  • Dynamitin
  • p50 dynamitin
  • RBP50

Background

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Dynactin Subunit 2/DCTN2/DCTN-50 Antibody (NBP2-16115)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Dynactin Subunit 2/DCTN2/DCTN-50 Antibody (NBP2-16115) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DCTN2
Entrez
Uniprot