DUSP22 Antibody - BSA Free

Immunohistochemistry-Paraffin: MKS1 Antibody [NLS6809] - Analysis of anti-DUSP22 antibody with human kidney.

• Reactivity: Hu, Bv, Eq, Pm, Pm, Rb, Mu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

DUSP22 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 aa peptide from near N-terminus of human DUSP22.
• Epitope: near N-terminus of human
• Specificity: Human DUSP22. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DUSP15 (59%).
• Predicted Species: Mouse (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DUSP22
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2 - 22 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Chicken (88%), Xenopus (82%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for DUSP22 Antibody - BSA Free

• dual specificity phosphatase 22
• dual specificity protein phosphatase 22
• EC 3.1.3.16
• EC 3.1.3.48
• FLJ35864
• homolog of mouse dual specificity phosphatase LMW-DSP2
• JKAP
• JNK-stimulating phosphatase 1
• JSP-1
• JSP1JNK-stimulatory phosphatase-1
• LMWDSP2
• LMW-DSP2
• Low molecular weight dual specificity phosphatase 2
• Mitogen-activated protein kinase phosphatase x
• MKP-x
• MKPXMAP kinase phosphatase x
• VHX

Background

MKPX, also known as JSP-1 for Jnk Stimulatory Phosphatase-1, belongs to the LMW-DSP subfamily of phosphatases. MKPX has been shown to have the capacity to activate the c-Jun N-terminal kinase (Jnk) signaling pathway. The activation of Jnk has been implicated in a number of important physiological processes, including embryonic morphogenesis, cell survival and apoptosis. At least two mRNA transcripts have been reported. Jnk signaling has been linked to human disease conditions, such as tumor development, cardiac hypertrophy, ischemia/reperfusion injury, diabetes, hyperglycemia-induced apoptosis, and several neurodegenerative disorders.MKPX has been shown to be widely expressed with highest expression in heart, kidney, liver, lung, pancreas and placenta. ESTs have been isolated from a diverse set of human tissues libraries, especially blood and breast.Caution: The acronym MKPX also has been used to describe Dual Specificity Protein Phosphatase 7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DUSP22
• Entrez:
  • 54903(Human)