DUOX2 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, CaSpecies Glossary
Applications WB, ICC/IF, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

DUOX2 Antibody [DyLight 550] Summary

Immunogen
Synthetic peptide made to an internal portion of human DUOX2 (within residues 400-500). [Swiss-Prot# Q9NRD8]
Localization
Apical cell membrane; Multi-pass membrane protein. Note: Localizes to the apical membrane of epithelial cells.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DUOX2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Paraffin
Application Notes
This DUOX2 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot. In Western blot a band is observed at ~150 kDa, and in Immunocytochemistry/Immunofluorescence membrane staining was seen in A431 cells. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24492313)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DUOX2 Antibody [DyLight 550]

  • dual oxidase 2
  • dual oxidase-like domains 2
  • EC 1.11.1.-
  • EC 1.6.3.1
  • flavoprotein NADPH oxidase
  • Large NOX 2
  • LNOX2P138(TOX)
  • Long NOX 2
  • NADH/NADPH thyroid oxidase p138-tox
  • NADPH oxidase/peroxidase DUOX2
  • NADPH thyroid oxidase 2
  • nicotinamide adenine dinucleotide phosphate oxidase
  • NOXEF2
  • p138 thyroid oxidase
  • P138-TOX
  • THOX2TDH6
  • Thyroid oxidase 2

Background

Dual oxidase 2 (DUOX2), a reduced NAD phosphate:O2 oxidoreductase flavoprotein, plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with hydrogen peroxide, which is required for hormone synthesis at the apical plasma membrane. The discovery of DUOX2 as a novel source of hydrogen peroxide in the digestive tract, particularly in the cecum and colon, makes it a new candidate mediator of physiopathological processes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt, Po, Ca
Applications: WB, ICC/IF, IHC-P

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DUOX2 Antibody (NB110-61576R). (Showing 1 - 1 of 1 FAQ).

  1. Hi, I am looking for an antibody to human DUOX2 that will work on human formalin fixed paraffin embedded sections. I notice from your website that you have several recommended for WB and wondered if you have any experience of their use in other areas?
    • At this time we do not have an antibody for DUOX2 that works in IHC paraffin embedded sections. If you choose to try one in this application we have our Innovator's Reward program where we reward our customers for trying antibodies in previously untested applications and species.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NB110-61576B
DyLight 488 Labeled NB110-61576G
DyLight 650 Labeled NB110-61576C
HRP Labeled NB110-61576H

Additional DUOX2 Products

DUOX2 NB110-61576R

Bioinformatics Tool for DUOX2 Antibody (NB110-61576R)

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Diseases for DUOX2 Antibody (NB110-61576R)

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Bioinformatics

Gene Symbol DUOX2