DUOX2 Products


Dual oxidase 2 (DUOX2), a reduced NAD phosphate:O2 oxidoreductase flavoprotein, plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with hydrogen peroxide, which is required for hormone synthesis at the apical plasma membrane. The discovery of DUOX-2 as a novel source of hydrogen peroxide in the digestive tract, particularly in the cecum and colon, makes it a new candidate mediator of physiopathological processes.

DUOX2 antibodies may be useful tools for thyroid hormone synthesis, hormonal regulation disorders, and certian types of cancer.


Entrez Human
Uniprot Human
Product By Gene ID 50506
Alternate Names
  • NADPH thyroid oxidase 2
  • EC
  • NADPH oxidase/peroxidase DUOX2
  • EC 1.11.1.-
  • NADH/NADPH thyroid oxidase p138-tox
  • nicotinamide adenine dinucleotide phosphate oxidase
  • Thyroid oxidase 2
  • flavoprotein NADPH oxidase
  • Long NOX 2
  • dual oxidase-like domains 2
  • Large NOX 2
  • NOXEF2
  • P138-TOX
  • LNOX2P138(TOX)
  • p138 thyroid oxidase
  • dual oxidase 2

Research Areas for DUOX2

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Lipid and Metabolism

Bioinformatics Tool for DUOX2

Discover related pathways, diseases and genes to DUOX2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related DUOX2 Blog Posts

Check out the latest blog posts on DUOX2.
Toll-like receptors in the intestinal epithelial cells
By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria...    Read more.
Read more DUOX2 related blogs.