Dtk/TYRO3 Antibody [DyLight 550] Summary
Synthetic peptide made to an internal portion of the human TYRO3 protein (within residues 100-250). [Swiss-Prot# Q06418]
Cell membrane; Single-pass type I membrane protein.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C in the dark.
DyLight 550 (A=562, E=576)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified
This TYRO3 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band can be seen at ~96 kDa.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Human and mouse. Immunogen sequence has 94% identity to rat.
Alternate Names for Dtk/TYRO3 Antibody [DyLight 550]
- EC 2.7.10
- EC 188.8.131.52
- TYRO3 protein tyrosine kinase
- Tyrosine-protein kinase byk
- Tyrosine-protein kinase DTK
- tyrosine-protein kinase receptor TYRO3
- Tyrosine-protein kinase RSE
- Tyrosine-protein kinase SKY
Receptor protein tyrosine kinases (RPTKs) are a class of transmembrane signaling molecules. They have been shown to regulate signaling cascades that control synaptic function in the central nervous system (CNS). Tyro3 is one of three RPTKs belonging to the Axl/UFO subfamily, that also includes Axl and Mer. Tyro3 is the most commonly expressed of these receptors in the CNS. It may be involved in the cell adhesion process, and is commonly found in adult tissues with expression mostly in brain, testis, vascular and lymphatic tissue.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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