DRAM Antibody (M3-P4B4) [FITC]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: M3-P4B4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

DRAM Antibody (M3-P4B4) [FITC] Summary

• Immunogen: Peptide Sequence - EKDYVYHVVS (amino acids 192 - 201)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DRAM1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DRAM Antibody (M3-P4B4) [FITC]

• Damage-regulated autophagy modulator
• DNA damage-regulated autophagy modulator protein 1
• DNA-damage regulated autophagy modulator 1
• DRAMFLJ11259

Background

DRAM is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DRAM1