DRAM Antibody (M3-P4B4) [DyLight 594]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: M3-P4B4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 594

DRAM Antibody (M3-P4B4) [DyLight 594] Summary

• Immunogen: Peptide Sequence - EKDYVYHVVS (amino acids 192 - 201)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DRAM1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DRAM Antibody (M3-P4B4) [DyLight 594]

• Damage-regulated autophagy modulator
• DNA damage-regulated autophagy modulator protein 1
• DNA-damage regulated autophagy modulator 1
• DRAMFLJ11259

Background

DRAM is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DRAM1