DPS Antibody

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Western Blot: DPS Antibody [NBP1-54645] - HepG2 cell lysate, concentration 5.0ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

DPS Antibody Summary

Immunogen
Synthetic peptides corresponding to PDSS1(prenyl (decaprenyl) diphosphate synthase, subunit 1) The peptide sequence was selected from the middle region of PDSS1. Peptide sequence GEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHE.
Specificity
This product is specific to Subunit or Isofrom: 1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDSS1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against PDSS1 and was validated on Western blot.
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for DPS Antibody

  • All-trans-decaprenyl-diphosphate synthase subunit 1
  • COQ1SPS
  • Decaprenyl pyrophosphate synthase subunit 1
  • decaprenyl-diphosphate synthase subunit 1
  • DPS
  • DPS1
  • EC 2.5.1.91
  • hDPS1
  • MGC70953
  • polyprenyl pyrophosphate synthetase
  • prenyl (decaprenyl) diphosphate synthase, subunit 1
  • RP13-16H11.3
  • subunit 1 of decaprenyl diphosphate synthase
  • TPRT
  • TPT 1
  • TPTcoenzyme Q1 homolog
  • trans-prenyltransferase (TPT)
  • Trans-prenyltransferase 1
  • trans-prenyltransferase

Background

PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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DPS NBP1-54645

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Bioinformatics

Gene Symbol PDSS1
Uniprot