Dopamine D2R/DRD2 Antibody

Images

 
Western Blot: Dopamine D2R/DRD2 Antibody [NBP2-88996] - MW marker (1) and 10ug of rat heart membrane extract (2) probed with Dopamine Receptor (D2) pAb at 4.0ug/ml.
Immunohistochemistry: Dopamine D2R/DRD2 Antibody [NBP2-88996] - Rat cerebral cortex. Neurons are labeled with Dopamine Receptor (D2) pAb in conjunction with Cy3 conjugated rabbit IgG antibody (H+L).
ELISA: Dopamine D2R/DRD2 Antibody [NBP2-88996] - HEK293 cells expressing dopamine receptor (D2) were treated with indicated concentrations of agonist (Quinpirol) and antagonist (Siperone) and probed with Dopamine ...read more
Western Blot: Dopamine D2R/DRD2 Antibody [NBP2-88996] - Dopamine D2R/DRD2 antibody [NBP2-88996]. Left image is the MW marker and right is two replicates of ~20 ug protein extract from one hemisphere of house sparrow ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, AvSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Dopamine D2R/DRD2 Antibody Summary

Immunogen
Synthetic peptide corresponding to the sequence near the N-terminus of mouse Dopamine D2R/DRD2.
Clonality
Polyclonal
Host
Rabbit
Gene
DRD2
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Western Blot
Theoretical MW
51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 4
using
NBP2-88996 in the following applications:

Reactivity Notes

Predicted species reactivity based on epitope sequence homology: rhesus macaque, chimpanzee, horse, arctic fox, dog, opossum, ferret. Avian reactivity reported from a verified customer review.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 50% glycerol
Preservative
0.01% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for Dopamine D2R/DRD2 Antibody

  • D(2) dopamine receptor
  • D2DR
  • D2R
  • Dopamine D2 R
  • Dopamine D2 receptor
  • Dopamine D2R
  • dopamine receptor D2 isoform
  • dopamine receptor D2
  • DRD2
  • seven transmembrane helix receptor

Background

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-89342
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, IP, WB
NBP2-73857
Species: Hu, Mu, Rt
Applications: CyTOF-ready, Flow, IHC, WB
AF6457
Species: Hu
Applications: WB
NBP2-45946
Species: Ca, Hu, Pm, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NB110-60017
Species: Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-)
Applications: ICC/IF, IHC-FrFl, IHC, IHC-Fr, WB
NBP2-22164
Species: Hu(-), Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
NBP3-12391
Species: Hu, Mu, Rt
Applications: DB, ELISA, ICC/IF, IP, WB
NBP1-00178
Species: Hu, Mu, Sh
Applications: Flow, ICC/IF, IHC, IHC-Fr, PEP-ELISA, WB
NLS3921
Species: Hu, Pm, Pm
Applications: IHC, IHC-P
NB100-1780
Species: Hu, Mu
Applications: Flow, PEP-ELISA, WB
NBP1-88927
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
AF682
Species: Hu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, Neut, WB
NBP1-89396
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NBP3-17255
Species: Hu
Applications: ICC/IF, WB
NBP3-15896
Species: Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-59069
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NB300-109
Species: Ch, Dr, Hu, I, Ma, Mu, Rt
Applications: Dual ISH-IHC, ICC/IF, IHC-FrFl, IHC-WhMt, IHC, IHC-Fr, IHC-P, KO, Simple Western, WB
H00006532-D01P
Species: Hu, Mu
Applications: WB
NBP1-87757
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, KD, WB
NBP2-26091
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA

Publications for Dopamine D2R/DRD2 Antibody (NBP2-88996) (0)

There are no publications for Dopamine D2R/DRD2 Antibody (NBP2-88996).
By submitting your publication information earn gift cards and discounts for future purchases.

Review for Dopamine D2R/DRD2 Antibody (NBP2-88996) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Avian and House sparrow.

Reviews using NBP2-88996:
Filter by Applications
WB
(1)
All Applications
Filter by Species
Avian and House sparrow
(1)
All Species
Images Ratings Applications Species Date Details
Western Blot Dopamine D2R/DRD2 NBP2-88996
Enlarge
4
reviewed by:
Melanie Kimball
WB Avian and House sparrow 06/16/2023
View

Summary

ApplicationWestern Blot
Sample TestedAdult brain
SpeciesAvian and House sparrow
Lot08202104

Comments

Comments***Novus Innovators Program - new species or application used on a primary antibody.***

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Dopamine D2R/DRD2 Antibody (NBP2-88996) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Dopamine D2R/DRD2 Products

Diseases for Dopamine D2R/DRD2 Antibody (NBP2-88996)

Discover more about diseases related to Dopamine D2R/DRD2 Antibody (NBP2-88996).
 

Pathways for Dopamine D2R/DRD2 Antibody (NBP2-88996)

View related products by pathway.

PTMs for Dopamine D2R/DRD2 Antibody (NBP2-88996)

Learn more about PTMs related to Dopamine D2R/DRD2 Antibody (NBP2-88996).
 

Research Areas for Dopamine D2R/DRD2 Antibody (NBP2-88996)

Find related products by research area.

Blogs on Dopamine D2R/DRD2

There are no specific blogs for Dopamine D2R/DRD2, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Melanie Kimball
06/16/2023
Application: WB
Species: Avian and House sparrow

Bioinformatics

Gene Symbol DRD2