DNase II Antibody

Images

 
Western Blot: DNase II Antibody [H00001777-B01P] - Analysis of DNASE2 expression in transfected 293T cell line by DNASE2 polyclonal antibody. Lane 1: DNASE2 transfected lysate(39.6 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: DNase II Antibody [H00001777-B01P] - Analysis of purified antibody to DNASE2 on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

DNase II Antibody Summary

Immunogen
DNASE2 (NP_001366.1, 1 a.a. - 360 a.a.) full-length human protein. MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI
Specificity
DNASE2 - deoxyribonuclease II, lysosomal,
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
DNASE2
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactivity against transfected lysate for WB. It has been used for IF and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DNase II Antibody

  • Acid DNase
  • Deoxyribonuclease II alpha
  • deoxyribonuclease II, lysosomal
  • deoxyribonuclease-2-alpha
  • DNase II alpha
  • DNase II, lysosomal
  • DNASE2A
  • DNL
  • DNL2
  • EC 3.1.22.1
  • Lysosomal DNase II
  • R31240_2

Background

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DNASE2
Entrez
Uniprot